Mouse models of human AML accurately predict chemotherapy response
نویسندگان
چکیده
منابع مشابه
Mouse models of human AML accurately predict chemotherapy response.
The genetic heterogeneity of cancer influences the trajectory of tumor progression and may underlie clinical variation in therapy response. To model such heterogeneity, we produced genetically and pathologically accurate mouse models of common forms of human acute myeloid leukemia (AML) and developed methods to mimic standard induction chemotherapy and efficiently monitor therapy response. We s...
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ژورنال
عنوان ژورنال: Genes & Development
سال: 2009
ISSN: 0890-9369
DOI: 10.1101/gad.1771409